Why Divinyl Sulfone (DVS) as crosslink?
November 23, 2023
MDAp®️ (Multiple Degree Amphiphilic Purification)
December 11, 2023
MBMT®️ (Micro Bead Monophasic Technology) by LifDerma introduces a groundbreaking approach to hyaluronic acid (HA) formulations. The technology ensures an elevated concentration of HA molecules, presenting a wholly viscous form of Hyaluronic Acid. The distinctive monophasic structure of MBMT®️ involves the formation of cross-links between all Hyaluronic Acid chains, resulting in a consistent gel-like composition. This stands in contrast to biphasic HA gels, where cross-linked HA forms a gel, and free HA molecules exist in its liquid phase.
Research indicates that monophasic HA formulations are characterized by enhanced stability and durability compared to their biphasic counterparts. Comparative studies, such as those conducted by Huang et al. in 2022, have demonstrated that monophasic HA fillers exhibit superior and more enduring aesthetic improvements, lower rates of post-injection discomfort, and a higher level of patient preference.
The Micro Bead Technology within MBMT®️ leverages the binding capability of Divynil Sulfone to create microbeads of HA. These microbeads form a connected array within a larger bead of HA, as illustrated in the accompanying image. This innovative design results in a higher concentration of Hyaluronic Acid Molecules per Bead, contributing to the overall efficacy of the technology.
